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Sfoglia per Soggetto "acute myeloid leukaemia"

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    • Molecular analysis of transferrin receptor mRNA expression in acute myeloid leukaemia 

      Kollia, P.; Stavroyianni, N.; Stamatopoulos, K.; Zoi, K.; Viniou, N.; Mantzourani, M.; Noguchi, C. T.; Paterakis, G.; Abazis, D.; Pangalos, C.; Loukopoulos, D.; Yataganas, X. (2001)
      Transferrin receptor (TfR, CD71) is an integral membrane glycoprotein that mediates cellular uptake of iron. In most tissues, TfR expression is correlated positively with proliferation and regulated at the post-transcriptional ...

    • Proliferation and bone marrow engraftment of AML blasts is dependent on beta-catenin signalling 

      Siapati, E. K.; Papadaki, M.; Kozaou, Z.; Rouka, E.; Michali, E.; Savvidou, I.; Gogos, D.; Kyriakou, D.; Anagnostopoulos, N. I.; Vassilopoulos, G. (2011)
      P>B-catenin is the central effector molecule of the canonical Wnt signalling pathway, which controls self-renewal of haematopoietic stem cells. Deregulation of this pathway occurs in various malignancies including myeloid ...